Personal care
Electric Toothbrush Replacement Heads: Match the Handle Family
Brush heads are recurring purchases with almost no research needed once you know the handle family. The connection system is the key.
Compatibility guide · Updated October 22, 2026Match your model to its refill
With Oral-B, identify the handle family before choosing bristle style. iO heads and the standard Genius, Smart, Pro and Vitality heads are different connection systems.
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Oral-B adult iO handle
Oral-B iO replacement heads
Look for iO on both the handle and replacement pack. A round head is not enough to establish fit; standard Oral-B heads are not the iO system.
Find Oral-B iO replacement heads on Amazon Oral-B handle and head compatibility →Oral-B Genius, Smart, Pro or Vitality handle
Standard Oral-B replacement heads
Choose a pack that names your handle family. Exclude iO heads; Oral-B explicitly lists them as incompatible with these handles. Compare the number of heads, not just the number of packs.
Find Standard Oral-B replacement heads on Amazon Oral-B handle and head compatibility →Have another model? Find its replacement
Find the right replacement
Find your model’s replacement
Enter the brand and model, or add a photo of the product label.
Fast rule: the exact model, cartridge or part code beats appearance. If the listing does not clearly name what you own, do not force the match.
Identify the handle family
Use the model name or number printed on the toothbrush handle or charging base. Search that exact family with “replacement heads” rather than relying on the brand alone.
Within a brand, older and newer handle systems may use different head connections. A familiar logo does not guarantee a physical fit.
Choose the head style after compatibility
Once fit is confirmed, compare the intended brushing style, head size and bristle design. Compatibility comes first; comfort and preference come second.
If you are replacing a head you already like, the simplest route is to match the name or code printed on the current package or head family.
Buy a pack size that stays clean in storage
Multi-packs are convenient for a recurring household item, especially when several people use compatible handles. Keep unused heads protected and dry.
Replacement intervals depend on wear and manufacturer guidance. Frayed or deformed bristles are a practical signal to check whether it is time for a fresh head.